Endogenous Cannabinoids Take the Edge off Neuroendocrine Responses to Stress

alzheimer’s disease; taking the edge off with cannabinoids

Alzheimer's disease; taking the edge off with cannabinoids?

Alzheimer's disease is an age-related neurodegenerative condition associated with cognitive decline. The pathological hallmarks of the disease are the deposition of beta-amyloid protein and hyperphosphorylation of tau, which evoke neuronal cell death and impair inter-neuronal communication. The disease is also associated with neuroinflammation, excitotoxicity and oxidative stress. In recent yea...

Estonian Genome Project - before the take-off and take-off

I will give an overview of the preparations of the EGP including all aspects of the project and current satus of the pilot phase, describe the informatics part of the project together with other aspects (legal, ethical, logistics, financial etc.) and where we stand in terms of population genetics and genotyping technology in order to start using the sample collection for case--control studies f...

Waiting for the Economy to take off

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Neural pathways link social support to attenuated neuroendocrine stress responses.

It is well established that a lack of social support constitutes a major risk factor for morbidity and mortality, comparable to risk factors such as smoking, obesity, and high blood pressure. Although it has been hypothesized that social support may benefit health by reducing physiological reactivity to stressors, the mechanisms underlying this process remain unclear. Moreover, to date, no stud...